In this work we review and analyze the various physical mechanisms that drive attenuation in hollow-core optical fibers. Numkam Fokoua, Eric, Abokhamis Mousavi, Seyed, Jasion, Gregory T. and Poletti, Francesco (2023) Loss in hollow-core fibers: mechanisms, scaling rules, and limits. Advances in Optics and Photonics, 15 (1). To simultaneously optimize two inherently conflicting performance metrics, namely, birefringence and confinement loss, a multi objective genetic algorithm is. omparable to those of standard silica-core single mode fibers at telecom wavelengths.